Preclinical Grade Plasmid DNA Preparation Services

 KMD Bioscience has been working on molecular biology research for many years. Plasmid vector is a powerful tool for genetic engineering. The quality of DNA obtained is critical factor for genetic experimentation. Our researchers have rich experience in plasmid extraction, we can provide comprehensive plasmid DNA preparation services from microgram- to gram-scale in order to meet different customers’ requirements.

With our upgraded DNA preparation platform, KMD Bioscience offers preclinical grade plasmid production with the most comprehensive and stringent quality specifications and analysis for preclinical project needs. All plasmids we manufactured guarantee strict quality control, to ensure that the highest quality product will be delivered to our customers. Preclinical grade plasmid DNA can be used in preclinical research such as vivo animal studies, from mice to non-human primates, gene therapy, cell therapy, and vaccine research, etc.


Service Process:



Quality Control:


 QC Items



Clear, no visible particles




100% alignment with reference sequence

Residual RNA

Non-detectable by gel electrophoresis

Genomic DNA

Non-detectable by gel electrophoresis

Residual Host Protein



90% supercoiled

Endotoxin Level


Restriction Analysis

Conforming to reference pattern

Bioburden Testing

No growth on agar plate after 48 hours




KMD Bioscience offers preclinical grade plasmid production:




Preclinical Grade

* Virus production

* DNA vaccines

* Preclinical animal studies


Delivery Results:


Delivery Content

Preclinical grade plasmid DNA products

Comprehensive QC report: including product appearance, A260/280, restriction enzyme analysis, endotoxin level, etc


Service Highlights:


--Rich experience in plasmid extraction

--Highly homogenous

--Quantitative bacterial DNA & protein analysis

--Perfect platform to ensure batch to batch consistency

--Quality-assured: Strict quality management, Endotoxin ≤10EU/mg

--Animal-Free production

--Microgram-to-gram-scale quantity, to meet various customers’ needs

--One-stop downstream services, including gene synthesis, custom cloning, or mutagenesis