Small Molecule Antigen & Antibody Development Service

KMD Bioscience has been working on antibody research for many years. Our scientific staff has extensive experience in antibody design and production, ensuring the best chance of getting a high affinity monoclonal antibody that works for your application. We can provide comprehensive antibody development services from antigen design through antibody purification with our well-established antibody engineering platform, aiming to provide customers with high-quality antibodies.

KMD Bioscience is a professional provider of antibody products and related services for food safety residues and trace levels anylasis. We can provide small molecule antigen & antibody development services. Our skilled team is glad to tailor or synthesize derivatives of small molecule compounds to meet the specific needs of our customers.

 

Small Molecule Antigen & Antibody:

 

Small molecules, or haptens do not have immunogenic but can induce antibody responses when coupled to carrier proteins. The hapten then reacts specifically with the antibodies generated against it to produce an immune or allergic response. Thus, although the hapten cannot elicit an antibody response on its own, it can bind with carrier and act as an antigen.

We have professors from Nankai University to assist our compound synthesis platform. After years of practice, we have accumulated rich experiences in small molecule coupling design and antibody production. We can now tailor or synthesize derivatives of small molecule compounds to meet the specific needs of our customers, providing haptens of different tethers or complete antigens with different carrier proteins. Currently, we can offer monoclonal antibody customization services based on two methods:

*Hybridoma based Antibody Customization Services

*Phage Display Library Technology

 

Service Content:

 

Packages

Carrier Type

Deliverable

Lead time

Hapten Modification

/

Modified small molecule derivatives

LC-MS result

1-2 weeks

Complete Antigen Production

*Bovine serum albumin (BSA)

*Ovalbumin (OVA)

*Keyhole limpet hemocyanin (KLH)

*Human Serum Albumin (HSA)

*Human gamma globulins

Complete antigen with SDS-PAGE, UV or MALDI-TOF identification results

1-2 weeks

Monoclonal Antibody Production

Antigen emulsification

Immunization

Cell fusion

Subcloning

Ascites production and antibody purification

Immunoassay results (including ELISA titer and specificity test results)

4-5 months

 

Application:

 

 

Service Highlights:

 

--Rich experience in monoclonal antibody development

--High affinity and specificity—pM grade

--Suitable for production of antibody with inactivated antigen

--Suitable for Immunohistochemistry of formaldehyde fixation

--Applicable to different levels of antibody screening protocols, such as epitope-specific antibody screening

--By using our FastAb Mouse Adjuvant, the antibody titer will peak after 3rd or 4th injection, decrease the immunization timeline and immunogen dosage

--One-stop downstream services, including antigen production, antibody development, ELISA kit development, etc

 

How to Order?

If you have any questions regarding our services or products, please feel free to contact us by E-mail: info.us@kmdbioscience.com or 

Hotline(1): +86-022-8216-4980; Hotline(2): +86-156-0119-0182

 

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