Nanoparticles

Non-porous spherical silica microspheres with large specific surface area, hydrophilic surface, good dispersion, and long-term stability in organic solvents and aqueous media. The hydroxyl group on the surface of the silica microspheres allows a variety of substances to be bound to the surface of the microspheres, realizing the chemical modification of them. Different functional groups can be introduced, such as carboxyl, amino and sulfhydryl, to make its surface functionalization; also can covalently bind a variety of biomolecules, such as biotin, streptavidin, etc., to improve its biological targeting, and be applied in bioanalysis, biochemical detection and other fields.

Product Number	Product Name	Surface Modification	Particle Diameter	Solid Content	Density	Preservative Fluid	Regular Packaging Specifications
KSM-SiOH	Silica Microbeads -SiOH	Silicon Hydroxyl	0.5μm-10μm	1.0%-10% w/v	2.0g/cm3	Pure water (0.05% w/v KMDsmb 300)	10/25/50mL
KSM-C	Silica Microbeads-COOH	Carboxyl	0.5μm-10μm	1.0%-10% w/v	2.0g/cm3	Pure water (0.05% w/v KMDsmb 300)	10/25/50mL
KSM-A	Silica Microbeads-NH2	Amino	0.5μm-10μm	1.0%-10% w/v	2.0g/cm3	Pure water (0.05% w/v KMDsmb 300)	10/25/50mL
KSM-S	Silica Microbeads-SH	Sulfhydryl	0.5μm-10μm	1.0%-10% w/v	2.0g/cm3	Pure water (0.05% w/v KMDsmb 300)	10/25/50mL
KSM-B	Silica Microbeads-Biotin	Biotin	0.5μm-10μm	1.0%-10% w/v	2.0g/cm3	Pure water (0.05% w/v KMDsmb 300)	10/25/50mL
KSM-SA	Silica Microbeads-Streptavidin	Streptavidin	0.5μm-10μm	1.0%-10% w/v	2.0g/cm3	Pure water (0.05% w/v KMDsmb 300)	10/25/50mL

Magnetic silica microspheres are strongly magnetically responsive, biocompatible magnetic beads that are stably dispersed in water and organic solvents to avoid swelling. The introduction of silicon dioxide shields the magnetic dipole interaction and improves its biocompatibility. The silica hydroxyl groups on the surface of the magnetic beads are able to specifically bind to nucleic acids in solution through hydrogen bonding and electrostatic interaction, allowing direct separation of nucleic acids from complex biological systems. At the same time, the surface Si-OH can make a variety of substances bound to the surface of the particle to achieve chemical modification. Different organic functional groups can be introduced, such as COOH, NH2, etc., to make its surface functionalized, and can also covalently bind A variety of biomolecules, such as Streptavidin, Biotin and Protein A, etc., to improve its biological targeting, and be applied in biological analysis, biochemical detection and other fields.

Product Number	Product Name	Surface Modification	ParticleDiameter	Concentration	Preservative Fluid	Regular Packaging Specifications
KMSM-SiOH	Magnetic silica microbeads-SiOH	Silicon Hydroxyl	0.25μm-6μm	10mg/mL-50mg/mL	DI Water/0.01M PBS (pH 7.4)	10mL
KMSM-C	Magnetic silica microbeads-COOH	Carboxyl	0.25μm-6μm	10mg/mL-50mg/mL	DI Water/0.01M PBS (pH 7.4)	10mL
KMSM-A	Magnetic silica microbeads-NH2	Amino	0.25μm-6μm	10mg/mL-50mg/mL	DI Water/0.01M PBS (pH 7.4)	10mL

Magnetic polymer microspheres have a sandwich structure, with an inner core of porous polymer microspheres and an outer polymer coating of different materials to meet different application requirements, with the magnetic material filling the pores between the two. The diameter of the microspheres ranges from 1.5 to 20 μm, and the particle size is highly homogeneous with a CV of less than 3.0%. The microsphere surface is a double-layer hydrophilic coating with very low surface non-specific adsorption, which is particularly suitable for the development of high-sensitivity bioassay methods, and has a wide range of applications in various fields of immunoassay and immune separation, which can be used in magnetic particles chemiluminescence, immunoprecipitation and co-precipitation, magnetic separation of cells, and nucleic acid-specific capture, and so on.

Product Number	Product Name	Surface Modification	Particle Diameter	Solid Content	Preservative Fluid	Regular Packaging Specifications
KMPM-C	Magnetic Polymer Microbeads-COOH	Carboxyl	1.5μm-20μm	1.0%-2.0% w/v	Pure water / Neutral buffer	5/10/25mL
KMPM-A	Magnetic Polymer Microbeads-NH2	Amino	1.5μm-20μm	1.0%-2.0% w/v	Pure water / Neutral buffer	5/10/25mL
KMPM-T	Magnetic Polymer Microbeads-Tosyl	Tolylsulfonyl	1.5μm-20μm	1.0%-2.0% w/v	Pure water / Neutral buffer	5/10/25mL
KMPM-SA	Magnetic Polymer Microbeads-Streptavidin	Streptavidin	1.5μm-20μm	1.0%-2.0% w/v	Pure water / Neutral buffer	5/10/25mL
KMPM-PA	Magnetic Polymer Microbeads-Protein A	Protein A	1.5μm-20μm	1.0%-2.0% w/v	Pure water / Neutral buffer	5/10/25mL

Magnetic agarose microspheres were produced by dispersing magnetic iron oxide nanoparticles around 10 nm in agarose microspheres with an agarose content of 6.0%. The agarose microspheres were all cross-linked internally, with a wide distribution of particle sizes between 40 -120 μm. The magnetic agarose microspheres are coupled with Protein A or Ni-NTA affinity ligands on the surface, which can be used in small-scale antibody/protein purification, immunoprecipitation, pull-down experiments and other scenarios. Magnetic agarose microspheres with other functional groups or unmodified are available as customized products.

Product Number	Product Name	Surface Modification	Particle Diameter	Solid Content	Preservative Fluid	Regular Packaging Specifications
KMA-C	Magnetic Agarose-COOH	Carboxyl	40μm-120μm	25% gel slurry	20% ethanol / neutral buffer	20mL
KMA-A	Magnetic Agarose-NH2	Amino	40μm-120μm	25% gel slurry	20% ethanol / neutral buffer	20mL
KMA-PA	Magnetic Agarose-Protein A	Protein A	40μm-120μm	25% gel slurry	20% ethanol / neutral buffer	20mL
KMA-PG	Magnetic Agarose-Protein G	Protein G	40μm-120μm	25% gel slurry	20% ethanol / neutral buffer	20mL
KMA-NN	Magnetic Agarose-Ni-NTA	Ni-NTA	40μm-120μm	25% gel slurry	20% ethanol / neutral buffer	20mL
KMA-GT	Magnetic Agarose-Glutathione	Glutathione	40μm-120μm	25% gel slurry	20% ethanol / neutral buffer	20mL
KMA-SA	Magnetic Agarose-Streptavidin	Streptavidin	40μm-120μm	25% gel slurry	20% ethanol / neutral buffer	20mL
KMA-LA	Magnetic Agarose-Lodoacetate	Lodoacetate	40μm-120μm	25% gel slurry	20% ethanol / neutral buffer	20mL

With its localized surface plasmon resonance phenomenon, gold nanoparticles have excellent optical properties, on the one hand, enhance the electromagnetic field around the gold nanoparticles to produce a strong bright spot, which can be applied to imaging, on the other hand, the incident energy is converted into heat to increase the local temperature around the near gold nanoparticles, which can be applied to photothermal therapy to assist the launch of the treatment, especially in the treatment of deep-seated tumors. At the same time, gold nanoparticles have better biocompatibility, lower biotoxicity and surface adsorption carrier ability, which can modify target molecules, drug molecules and imaging contrast agents and other functional molecules, and functionalized gold nanoparticles have applications in cell induction, drug carriers, therapeutic methods, clinical diagnosis, and antibody labeling.

Product Number	Product Name	Surface Modification	Optical Density (A.U)	Buffer solution	Particle Diameter	Particle Diameter Dispersion (+ / -nm)	Regular Packaging Specifications
KSGN	Non-Functionalized Standard Gold Nanoparticles	Tannic acid	1OD	DI water/0.01M PBS (pH 7.4)	5-100	CV%<12%	0.5/1mL
KSGN	Non-Functionalized Standard Gold Nanoparticles	Citric acid	1OD	DI water/0.01M PBS (pH 7.4)	5-100	CV%<12%	0.5/1mL
KGN-PA	Gold Nanoparticles-Protein A	Protein A	3OD	DI water/0.01M PBS (pH 7.4)	5-100	CV%<12%	0.5/1mL
KGN-PG	Gold Nanoparticles-Protein G	Protein G	3OD	DI water/0.01M PBS (pH 7.4)	5-100	CV%<12%	0.5/1mL
KGN-SA	Gold Nanoparticles-Streptavidin	Streptavidin	3OD	DI water/0.01M PBS (pH 7.4)	5-100	CV%<12%	0.5/1mL
KGN-B	Gold Nanoparticles-Biotin	Biotin	50OD	DI water/0.01M PBS (pH 7.4)	5-100	CV%<12%	0.5/1mL
KCGN-3K	Carboxyl-PEG Linker Gold Nanoparticles-3K	Carboxyl	50OD	DI water/0.01M PBS (pH 7.4)	5-100	CV%<12%	0.5/1mL
KCGN-5K	Carboxyl-PEG Linker Gold Nanoparticles-5K	Carboxyl	50OD	DI water/0.01M PBS (pH 7.4)	5-100	CV%<12%	0.5/1mL
KAGN-3K	Amine-PEG Linker Gold Nanoparticles-3K	Amine	50OD	DI water/0.01M PBS (pH 7.4)	5-100	CV%<12%	0.5/1mL
KAGN-5K	Amine-PEG Linker Gold Nanoparticles-5K	Amine	50OD	DI water/0.01M PBS (pH 7.4)	5-100	CV%<12%	0.5/1mL

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