Antibody Platform

KMD Bioscience has built up a mature antibody production platform. With our well-established antibody engineering technology, we can provide comprehensive antibody production services including antigen design, peptide synthesis, gene expression, immunization, antibody purification, identification and antibody labeling.

 

Monoclonal Antibody Development Services:

 

KMD Bioscience has been working on antibody development for many years. we can provide monoclonal antibody development services based on two methods:

1. Cell fusion technique: including mouse hybridomas, mouse/rat, mouse/guinea pig cell fusion, and fully humanized hybridoma to produce monoclonal antibodies.

2. Phage display library construction technique. With our professional phage display antibody library technology, we can generate antibody libraries and select high-affinity antibodies.

 

Polyclonal Antibody Development Services:

 

 KMD Bioscience has extensive experience in protein expression and antibody production, we can provide polyclonal antibody production for the following species: rabbit, mouse, chicken, sheep, goat, donkey, alpaca and bovine polyclonal antibody.

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Antibody Sequencing and Application Platform:

 

With the extensive expertise in the antibody research, we can provide comprehensive antibody downstream engineering services to meet different customers’ needs.

 

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Antibody Purification Services

We provide various antibody purification methods such as protein A/G affinity purification, antigen affinity purification, etc.

Antibody Pairing (Custom ELISA Assay Development)

Antibody pairing is critical for the development of ELISA kits. Our antibody staffs have extensive experience in developing clinical assays and can provide comprehensive enzyme-linked immunoassay kit development services, including detection sensitivity verification, linear range verification, repeatability verification, specificity verification and thermal stability (37 °C or 25 °C thermal stability) verification. We have successfully developed a small molecule detection kit with a detection sensitivity of 0.1 ppb.

Antibody Sequencing Services

KMD Bioscience uses the most advanced Orbitrap Fusion Lumos mass spectrometer and powerful antibody sequencing data processing software, combined with gene sequencing and bioinformatics database, established a new generation of antibody sequencing platform to achieve fast and accurate analysis of antibody primary structure, thus ensuring the sequencing accuracy of each antibody. 

Antibody Modification Services

Immunological testing usually involves the modification of antibodies. Our scientists can provide high-quality antibody labeling services, including fluorescent molecular markers (FITC, FAM, etc.), vector coupling (agarose beads, magnetic bead coupling, etc.), enzyme labeling (HRP, AP, etc.).

Antibody & Antigen Binding Kinetics Study 

We can provide our clients with BIAcore-based antibody affinity verification services for the development of vaccine assays that can be used to assess the immunogenicity of antigens in animals in vitro. In addition, it can solve the problem of difficulty in selecting different antibodies against the same antigen in the process of vaccine development and the determination of antibody affinity in the rapid detection method.

 

Service Highlights:

 

--Rich experience in protein expression and antibody development

--Competitive pricing for high quality

--Mature antibody and recombinant protein platform

--Strict quality assurance: cGMP management rules

--Fast and reliable delivery speed

--One-stop services, including antigen preparation, antibody development, phage library construction, antibody modification and related services